Alternative Synthesis of the Pesticide Carbaryl
Faculty Mentor(s) Name(s)
Ronald Okoth
Abstract
Carbaryl is a wide-spectrum synthetic insecticide used outdoors to control a wide variety of insect pests both in largescale farms and in small gardens and lawns. Unfortunately, the synthesis route used in the industrial production of carbaryl requires the use of the highly toxic and poisonous methyl isocyanate (MIC). Due to the toxicity of MIC, the synthesis of carbaryl and its derivatives poses a huge challenge for teaching and research labs curtailing structure and activity studies. The synthesis of carbaryl we propose here avoids the use of MIC and should allow for access to a wide variety of N-derivatives of carbaryl. Carbaryl was obtained via a 4-nitrophenyl carbamate intermediate in a two-step reaction. The synthesized carbaryl was spectroscopically comparable to carbaryl isolated from commercially available Sevin® insecticide
Start Date
27-3-2024 10:00 AM
End Date
27-3-2024 10:50 AM
Location
Magnolia Ballroom
Alternative Synthesis of the Pesticide Carbaryl
Magnolia Ballroom
Carbaryl is a wide-spectrum synthetic insecticide used outdoors to control a wide variety of insect pests both in largescale farms and in small gardens and lawns. Unfortunately, the synthesis route used in the industrial production of carbaryl requires the use of the highly toxic and poisonous methyl isocyanate (MIC). Due to the toxicity of MIC, the synthesis of carbaryl and its derivatives poses a huge challenge for teaching and research labs curtailing structure and activity studies. The synthesis of carbaryl we propose here avoids the use of MIC and should allow for access to a wide variety of N-derivatives of carbaryl. Carbaryl was obtained via a 4-nitrophenyl carbamate intermediate in a two-step reaction. The synthesized carbaryl was spectroscopically comparable to carbaryl isolated from commercially available Sevin® insecticide